Patients affected by more severe cases of gum disease often suffer from jaw bone and tooth loss. At the site of an extraction or missing tooth, the jaw bone begins to degrade over time, which deteriorates the supporting structures of the teeth. This puts surrounding teeth at risk of becoming loose, shifting or falling out. Guided Tissue Regeneration (GTR) is a process that uses a combination of membranes and tissue-stimulating proteins to regenerate the bone and tissue structures. This helps to restore natural look and function to the smile, and protects it from further harm.